Topic: Green chemistry

Author: Franziska Emmerling
Lecture on mechanochemistry for MSC and BSC students on a regular basis.

Author(s): Carlos Fernández and IMPACTIVE.
Carlos Fernández, scientific leader at the European project ETERNAL, explains all about this project and its objective: the reduction of the environmental impact of pharmaceutical products throughout their entire life cycle. This webinar is part of the IMPACTIVE webinar, which explores mechanochemistry, green pharmaceuticals, and green chemistry.

Author(s): Evelina Colacino and IMPACTIVE.
The first edition of the IMPACTIVE webinar series, featuring Evelina Colacino, IMPACTIVE project coordinator. In it, she explains all about the project and how mechanochemistry can help address shortages in the European pharmaceutical supply chain.

Author: IMPACTIVE.
Mechanochemistry is a groundbreaking field, revolutionizing chemistry through force-triggered reactions, eco-friendly practices, and efficient processes. It’s a pioneer technology with applications across multiple fields: biomass transformation, energy storage, agrochemicals, and much more. With its versatility and sustainability, it’s reshaping a myriad of industries towards a greener, more innovative future.

Author: Sanità 33.
Evelina Colacino, IMPACTIVE project coordinator, is interviewed by the Italian media outlet Sanità 33. The discussion focuses on pharmaceutical sustainability, specifically on pharmaceutical synthesis and her work on developing molecules without the use of solvents.

Author: Ruhr University Bochum.
Interview with Bulgarian chemist Desislava Dobreva, one of the founders of the start-up Mechanolution. The aim of the start-up is to make chemical synthesis more environmentally friendly.

Author: IMPACTIVE.
Grinding stuff sounds simple. In fact, it’s oddly one of the oldest ways to carry out chemical reactions. And, although solvent-based chemistry still dominates the industry, mechanochemistry –transformations enabled by mechanical force– experiences a new surge, an exciting era of rediscovery. Inspired by the 12 principles of green chemistry, mechanochemistry could really reshape chemical and pharmaceutical manufacturing.

Author(s): Evelina Colacino, Gandrath Dayaker, Alain Morère and Tomislav Friščić.
This education article describes a solvent-free mechanochemical synthesis in an undergraduate chemistry teaching laboratory. As a model reaction, the experiment addresses the catalytic mechanochemical synthesis of a small library of sulfonylureas, including a known active pharmaceutical ingredient, tolbutamide.