Filter by:
This paper reports the first application of bead-mill technology (Dyno®-mill) for the sustainable mechanochemical synthesis of Paracetamol.
This study pioneers the use of a drum mill for pharmaceutical co-crystal synthesis, using rac-ibuprofen:nicotinamide as a representative example.
Author: Sanità 33.
Evelina Colacino, IMPACTIVE project coordinator, is interviewed by the Italian media outlet Sanità 33. The discussion focuses on pharmaceutical sustainability, specifically on pharmaceutical synthesis and her work on developing molecules without the use of solvents.
Author: Ruhr University Bochum.
Interview with Bulgarian chemist Desislava Dobreva, one of the founders of the start-up Mechanolution. The aim of the start-up is to make chemical synthesis more environmentally friendly.
Edited by: Evelina Colacino , Guido Ennas , Ivan Halasz , Andrea Porcheddu and Alessandra Scano.
This book focuses on the rediscovery of mechanochemistry for inorganic, organic and organo-metallic materials. Focus on experimental techniques and equipment will show how to implement mechanochemistry as an innovative way to sustainability in academic laboratories. The contents are ideal for researchers starting off in industry and academia, as well as advanced students.
Author(s): Evelina Colacino, Gandrath Dayaker, Alain Morère and Tomislav Friščić.
This education article describes a solvent-free mechanochemical synthesis in an undergraduate chemistry teaching laboratory. As a model reaction, the experiment addresses the catalytic mechanochemical synthesis of a small library of sulfonylureas, including a known active pharmaceutical ingredient, tolbutamide.